Pre-formed Donor-specific Alloantibodies (DSA) Detected Only by Luminex Technology Using HLA-coated Microspheres and Causing Acute Humoral Rejection and Kidney Graft Dysfunction.
Muro M, Llorente S, Gónzalez-Soriano MJ, Minguela A, Gimeno L, Alvarez-López MR.
Clinical Transplants 2006, Chapter 28
The different methodologies for the detection of HLA sensitization could have discrepant results. At the moment, luminex technology seems--in our opinion--to be the most sensitive and safest method for antibody detection, and it should be taken into account during the transplantation process and as a means of indicating immunossuppresive regimen modulation.