Antibody-mediated Rejection: A Single Center Experience at Tokyo Women's Medical University.

Tanabe K, Ishida H, Omoto K, Shimizu T, Shirakawa H.

Clinical Transplants 2006, Chapter 26

Abstract

AMR is one of the most important risk factors for long-term graft loss and obviously prevention of AMR would be a most effective treatment to obtain excellent long-term graft survival. We can now detect low levels of anti-HLA antibodies using solid-phase and bead-based assays and our data show that these low levels f anti-HLA antibodies, especially DSA, could be a very important marker for AMR after renal transplantation. Once we can detect these antibodies, we have effective means to desensitize the patients prior to renal transplantation.