What we do:
Focus on Ending Transplant Failure
We must develop a stronger understanding of antibody mediated injury in transplant and develop new diagnostic and therapeutic tools to eradicate this problem in transplant. Here at the Terasaki Research Institute, we are working to make this happen. Our scientists will work to develop a stronger understanding of antibody mediated injury in transplant and develop new diagnostic and therapeutic tools to eradicate this problem in transplant. We will do work in three key research areas: epidemiological research, novel diagnostic/biomarker development, new prevention and therapeutic strategies.
LEARNING THROUGH DATA
Through our many collaborations, including our largest - Multicenter Transplant Alliance consortium, we will gather data and use this data to discover a new clarity of allograft rejection and failure. Bringing a very large number of patients and an even larger number of data points into one system, we will be able to use big data science to model, learn, and advance the innovation and discovery process in transplantation.
DEVELOPING AND IMPLEMENTING NEW TECHNOLOGY
We will develop new or improved diagnostic tools using advanced technology. We will begin with developing new testing technologies to better understand the problem of antibodies. In addition, we will be conducting translational research to develop tests that can indicate allograft injury or immune activation. Finally, we are focused on developing companion diagnostic tools that can better guide therapies used to eradicate or halt alloantibody mediated injury.
And finally, at the Terasaki Research Institute, we will be actively developing new ways to treat and prevent rejection in transplant. Our research and development team is working to develop new therapeutic medications, approaches, and regimens that can solve the problem of chronic rejection. In addition, through the Multicenter Transplant Alliance consortiums (MTA-K, MTA-P, and MTA-L) we will work to bring these and other new therapies to transplant faster.