Vadim Jucaud, Ph.D.
Dr. Vadim Jucaud is an Assistant Professor at the Terasaki Institute. Dr. Jucaud has been part of the Terasaki Laboratory since 2010, where he started his research career under the mentorship of Professor Paul I. Terasaki in the fields of histocompatibility and immunogenetics, with a particular emphasis on HLA antibodies and the Humoral Theory of Transplantation.
Dr. Jucaud has a Ph.D. in Immunology and Microbiology, specializing in transplant immunology and Human Leukocyte Antigen (HLA) immunobiology, notably in the diversity, detection, and prediction of the humoral response against HLA molecules. Dr. Jucaud is an expert in HLA immunogenetics, histocompatibility, and immunogenicity, with excellent technical skills forged by 12 years of experience in characterizing the humoral immune response in transplant patients, T and B cell immunomodulation, sensitive multiplex immunoassays, antibody cross-reactivity and immunogenic antibody epitopes, and HLA antibody/antigen interactions. Dr. Jucaud received the American Transplant Congress Young Investigator Award in 2018 for his outstanding work demonstrating the prevalence and impact of de novo donor-specific antibodies during a multicenter immunosuppression withdrawal trial in adult liver transplant recipients.
With the establishment of TIBI in 2020, Dr. Jucaud has been leading the organs-on-a-chip and biosensors team. Motivated by his background and the exciting multidisciplinary research at the Terasaki Institute, Dr. Jucaud is proposing a unique approach to combine HLA immunobiology, organ-on-a-chip technologies, tissue engineering, biomaterials, and biosensors for developing novel immunocompetent organs-on-a-chip platforms and microphysiological systems. The long-term objective of Dr. Jucaud's lab is to engineer innovative in vitro models recapitulating complex biological mechanisms of organ physiology and disease states to be considered by regulatory authorities as an indispensable step in accelerating drug discovery and development pipelines and promoting personalized medicine applications while reducing the need for animal model testing.
Dr. Vadim Jucaud’s Lab is recognized for its vibrant and collaborative research environment, where multidisciplinary teams thrive and innovation flourishes. With access to state-of-the-art facilities and cutting-edge equipment, scientists in the lab are empowered to push the boundaries of scientific discovery in four major research thematic areas:
(1) Organ on-a-chip technologies;
(2) Organ transplantation;
(3) Biosensors and biomarker detection;
(4) Biomaterials.
These research thematics seamlessly overlap, thus fostering a holistic approach to advancing biomedical innovation. Dr. Jucaud has authored 67 peer-reviewed publications and 45 conference abstracts, with an h-index of 24 and over 1,725 citations.
