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  • Self-plugging Microneedles Offer Potential to Improve Delivery of Drugs into the Eyeball

    Published research on new eye treatment delivery shows improvement over hypodermic needles



    June 17, 2022

    (LOS ANGELES)
    – A collaborative team, including scientists from the Terasaki Institute for Biomedical Innovation (TIBI), has developed a novel, self-plugging microneedle for injecting therapeutics into the eyes, potentially solving one of the major challenges of treating eye diseases – accurate delivery of therapeutic drugs to the retina, while guarding against possible complications at the injection site.

  • Repairing Tendons with Silk Proteins



    May 3, 2022

    (LOS ANGELES)
    – Just mentioning a ruptured Achilles tendon would make anyone wince. Tendon injuries are well known for their lengthy, difficult and often incomplete healing processes. Sudden or repetitive motion, experienced by athletes and factory workers, for example, increases the risk of tears or ruptures in the tendons; thirty percent of all people will have a tendon injury, with the risk being highest in women. What’s more, those who suffer from these injuries are more prone to further injuries at the site or never recover fully.

  • Flexible Printable Electrical Patches for Accelerated Wound Healing

    Flexible, antibacterial conductive hydrogel-ePatch enables personalized, high efficiency wound treatment



    April 19, 2022

    (LOS ANGELES)
    – There are myriad ways in which people can experience physical wounds – from minor scrapes and abrasions to the effects of surgery, critical injuries, burns and other major traumas. The healing process for these wounds can also vary among individuals and may be adversely affected by underlying health conditions such as vascular insufficiencies, diabetes, obesity and advanced age. In severe cases, abnormal wound healing processes can result in chronic wounds, a condition which can dramatically affect mobility, quality of life and healthcare costs.

  • Localized Melanoma Treatment Using pH-Dependent Drug Delivery



    March 24, 2022

    (LOS ANGELES)
    – In chemotherapeutic treatment of localized malignant tumors, it is desirable to administer targeted, controlled delivery of anti-tumor drugs. As these tumors are known to exist in an acidic environment, it is also desirable that these delivery methods be responsive to pH and that the drugs are released in a pH-dependent manner.

  • Decreasing Cancer Drugs’ Side Effects

    Scientists develop plant-based “hairy nanocrystals” to remove excess chemotherapy drugs from the blood



    January 6, 2022

    (LOS ANGELES)
    – Millions of people around the globe are affected by cancer each year; more than 39% of men and women are diagnosed with cancer during their lifetime. Chemotherapy is the most commonly employed, standard cancer treatment and targeted delivery of these drugs to the tumor site increases their effectiveness. However, excess drugs may still circulate to the rest of the body and cause multiple side effects, including anemia, chronic infections, hair loss, jaundice and fever.

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