Core Platform
Vascularized Tissueoids
Perfusable human tissue models engineered for disease modeling, drug screening, immune interrogation, and precision medicine.
Vadim Jucaud Laboratory
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Vadim Jucaud, Ph.D. Principal Investigator Abdul R.C. Salih, Ph.D. Post-Doctoral Fellow Megha Saha, M.S. Research Associate Arne Peirsman, M.D., Ph.D. Post-Doctoral Fellow Danial Khorsandi, Ph.D. Post-Doctoral Fellow Satoru Kawakita, M.S. Data Scientist Bryan Hatherley, B.S. Research Associate Everardo Jauregui, B.S. Master's Student
Platform Systems
Organ-on-Chip & MPS
Microphysiological systems that recreate dynamic human biology with controlled flow, interfaces, and tissue architecture.
Immune Biology
Transplant Immunology
Human-relevant platforms to study HLA biology, alloimmunity, rejection, tolerance, and graft injury.
Engineering
Biomaterials & Engineering
Engineered matrices and device architectures that support vascularization, function, and tissue-specific performance.
Oncology
Cancer Biology
Tissueoid models for tumor progression, immune interactions, therapeutic response, and microenvironment-driven behavior.
Real-Time Readouts
Biosensors & Monitoring
Integrated sensing technologies for real-time tracking of biological activity, secreted factors, and treatment response.
Translation
Disease Modeling
Translational systems for studying liver injury, inflammation, regenerative biology, and patient-relevant interventions.
0Peer-Reviewed Publications
0Google Scholar Citations
0Conference Abstracts
0H-Index
About
Translational immunology, organ-on-chip, and precision medicine
Dr. Vadim Jucaud is an immunologist and biomedical engineer whose work sits at the intersection of organ-on-a-chip technology, transplant immunology, and translational medicine.
Building on a foundation in HLA immunogenetics, antibody biology, microfluidics, biomaterials, and biosensing, VJLabs develops vascularized Tissueoids and immune-competent microphysiological systems for drug discovery, disease modeling, and personalized medicine.
Research Funding · $6M+ Secured
Active: NIH R01 ($2.3M, organ transplantation organ-on-chip), NIH R21 ($500K, xenotransplantation organ-on-chip), Mayo Clinic Partnership ($1.6M, transplant innovation)
Completed: NIH R21 ($500K, allograft rejection organ-on-chip), METAvivor ($100K, metastatic breast cancer), OpenWater ($1M, industry collaboration)
News & Highlights
Latest from VJLabs
VJLabs Awarded NIH R21 Grant for Xenotransplantation Research
VJLabs has been awarded an NIH R21 grant to advance xenotransplantation research using organ-on-a-chip technology.
Read more New Vascularized Tissueoid-on-a-Chip for Liver Regeneration and Transplant Rejection
VJLabs published a milestone paper in Advanced Materials on our immunocompetent liver Tissueoid platform.
Read more Strengthening Global Ties: Royal Belgian Economic Mission & Ghent University
The Terasaki Institute welcomed the Royal Belgian Economic Mission and Ghent University, strengthening international collaboration in biomedical innovation.
Read more TIBI and CSUN Launch Partnership for Biomedical Research Education
The Terasaki Institute and Cal State Northridge launched a new partnership to advance biomedical research education and training.
Read more 3D Microphysiological System Modeling Pericyte-Induced Chemoresistance in Glioblastoma
VJLabs developed a 3D microphysiological system that models pericyte-induced temozolomide resistance in glioblastoma.
Read more Advancing Monoclonal Antibody Biomanufacturing
A new microfluidic-based biosensing platform for real-time monitoring of monoclonal antibody cellular secretion, developed with UT San Antonio.
Read more Novel Liver Cancer-on-a-Chip Model for Embolic Agent Testing
A human vascularized liver cancer-on-a-chip model to evaluate vessel remodeling and cell death in response to embolic agents.
Read more Cancer Vaccine Testing in Aging Populations
A new organ-on-a-chip platform recapitulating age-dependent immune responses for evaluating cancer vaccine performance in older adults.
Read more $2.3 Million NIH Grant for Organ Transplantation Research
The Terasaki Institute was awarded a $2.3 million grant from NIH for organ transplantation research using organs-on-a-chip technology.
Read more Mayo Clinic & Terasaki Institute Launch Collaboration for Transplant Innovation
Mayo Clinic and the Terasaki Institute launched a collaboration to advance transplant innovation through organ-on-a-chip technologies.
Read more Remembering the Legacy of Dr. Paul I. Terasaki
Dr. Jucaud delivered a talk celebrating his mentor's life and moderated a Fireside Chat with leaders from UCLA, Cedars-Sinai, and One Lambda.
Read more NIH Grant to Develop Allograft-Rejection-on-a-Chip Model
TIBI received an NIH grant to develop an allograft rejection-on-a-chip model for studying immune-mediated graft injury.
Read more Screen-Printed Electrodes for Measuring Endothelial Barrier Integrity
Development of screen-printed electrodes for real-time TEER measurement of endothelial barrier integrity in organ-on-a-chip devices.
Read more
TIBI Awarded Grant from METAvivor
The Terasaki Institute received a grant from METAvivor to support metastatic breast cancer research.
Read more0Original Research Papers
0Review Articles
0Conference Abstracts
0Google Scholar Citations
Original Research
Research papers
- 2026 · Advanced MaterialsSalih ARC, Peirsman A, Khorsandi D, Ferrao R, Ferreira L, Kamaraj M, John JV, Baquerizo A, Jucaud V. Liver Tissueoid on-a-Chip Modeling Liver Regeneration and Allograft Rejection.
- 2025 · ACS SensorsTang RC, et al. Rapid Point-of-Care Inflammatory Cytokine Monitoring during Normothermic Liver Perfusion via a Multiplexed Paper-Based Vertical Flow Assay.
- 2025 · Lab on a ChipMaity S, Hassani Najafabadi A, et al. Lymph node paracortex-inspired on-a-chip recapitulating immunosenescence.
- 2025 · BioengineeringHernandez AL, et al. Continuous Optical Biosensing of IL-8 Cancer Biomarker Using a Multimodal Platform.
- 2025 · Biosensors and BioelectronicsKhorsandi D, Yang JW, et al. Real-Time and Label-Free Monitoring of Monoclonal Antibody Secretion Rates Using a PC-TIR Biosensor.
- 2025 · BiofabricationNguyen HT, et al. Embolization-on-a-chip: Novel Vascularized Liver Tumor Model for Evaluation of Cellular and Cytokine Response to Embolic Agents.
- 2025 · Acta BiomaterialiaMaity S, Jewell C, et al. Deciphering pericyte-induced temozolomide resistance in glioblastoma with a 3D microphysiological system.
- 2025 · SmallJoshi A, et al. FLight Biofabrication of Aligned Fibrillar Structures to Direct 3D Cell Organization Within Microgels.
- 2024 · ACS NanoKamaraj M, et al. Granular Porous Nanofibrous Microspheres Enhance Cellular Infiltration for Diabetic Wound Healing.
- 2024 · SmallYang JW, Khorsandi D, et al. Liver-on-a-Chip Integrated with Label-Free Optical Biosensors for Rapid and Continuous Monitoring of Drug-Induced Toxicity.
- 2023 · Biomedical MicrodevicesKawakita S, et al. Rapid integration of screen-printed electrodes into thermoplastic organ-on-a-chip devices for real-time monitoring of TEER.
- 2020 · Scientific ReportsKawakita S, Beaumont JL, Jucaud V, Everly MJ. Personalized prediction of delayed graft function for recipients of deceased donor kidney transplants.
- 2020 · J Immunol MethodsJucaud V, et al. Validation and cross-reactivity pattern assessment of monoclonal antibodies for donor-specific IgG antibody subclasses.
- 2019 · HepatologyJucaud V, Shaked A, et al. Prevalence and Impact of De Novo Donor-Specific Antibodies During a Multicenter Immunosuppression Withdrawal Trial.
- 2017 · TransplantationJucaud V, Ravindranath MH, Terasaki PI. Conformational Variants of the Individual HLA-I Antigens on Luminex Single Antigen Beads.
Reviews & Abstracts
Reviews and conference output
Review papers
- 2025 · Nano ResearchMohaghegh N, et al. Immunoengineering strategies using nanoparticles for obesity treatment.
- 2025 · Science of The Total EnvironmentBurd BS, et al. Can the insects Galleria mellonella and Tenebrio molitor be the future of plastic biodegradation?
- 2024 · SmallMaity S, et al. Recent Developments in Glioblastoma-On-A-Chip for Advanced Drug Screening Applications.
- 2024 · RSC Book ChapterKhorsandi D, et al. Lab-on-a-chip: Unit Operations to Scale-up Strategies.
- 2024 · AntibodiesJucaud V. Allogeneic HLA Humoral Immunogenicity and the Prediction of Donor-Specific HLA Antibody Development.
Conference abstracts
- 48 conference abstractsOngoing dissemination across transplantation, organ-on-chip, biomaterials, biosensing, and microphysiological systems meetings.
- Research themesVascularized Tissueoids, liver regeneration, allograft rejection, xenotransplantation, cancer immunology, TEER monitoring, and real-time biosensing.
- Scientific translationConference work supports collaborations, grant programs, and development of clinically relevant human tissue models.
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Contact
Connect with VJLabs
Terasaki Institute for Biomedical Innovation
21100 Erwin Street, Woodland Hills, CA 91367
Vascularized Tissueoids, organ-on-chip, transplant immunology, biosensing, biomaterials, and disease modeling.
Opportunities
Join, collaborate, or follow our work
We welcome inquiries from prospective postdoctoral fellows, graduate students, research associates, interns, and collaborators interested in translational bioengineering and precision medicine.
- Who we are looking forResearchers excited by organ-on-chip systems, immunology, microfluidics, biomaterials, biosensing, and disease modeling.
- How to reach outSend a concise email with your CV, area of interest, and why VJLabs is a fit.
Vadim Jucaud, Ph.D. Principal Investigator 
Abdul R.C. Salih, Ph.D. Post-Doctoral Fellow 
Megha Saha, M.S. Research Associate 
Arne Peirsman, M.D., Ph.D. Post-Doctoral Fellow 
Danial Khorsandi, Ph.D. Post-Doctoral Fellow 
Satoru Kawakita, M.S. Data Scientist 
Bryan Hatherley, B.S. Research Associate 
Everardo Jauregui, B.S. Master's Student Human tissue models for precision medicine
Vascularized Tissueoids · Organ-on-Chip · Biosensing
Research built around vascularized Tissueoids
Tissueoids · Immunology · Microphysiological systems · Biosensing · Biomaterials
Vadim Jucaud, Ph.D.
Assistant Professor · Founder of VJLabs · Terasaki Institute
Research output and publication record
Original research · Reviews · Conference abstracts · Google Scholar
The people behind VJLabs
An interdisciplinary team advancing tissue engineering and translational immunology
Connect with VJLabs
Collaborations · Opportunities · Scientific inquiries