News

Wearable Pressure-Sensitive Devices for Medical Use

October 16, 2020

Novel design and strategic use of materials in a pressure-sensitive adhesive strip

(LOS ANGELES) – In recent years, the use of wearable sensing devices has become a part of people’s everyday lives.  Devices such as smart watches, for example, can be used to monitor physical fitness functions such as heart rate, sleep and exercise. 

But advances in technology have opened many more possibilities for monitoring patient health.  Sensors can now measure important health indicators such as metabolites, oxygen or therapeutic drug levels in the blood using wearable or hand-held devices.  This allows patients an easy method of performing continuous, less invasive, real-time testing at home for diagnostic or treatment purposes.  Having such a system profoundly impacts both patient and caregivers’ needs, decreasing the requirement for frequent hospital appointments and encouraging compliance with treatment.

Microneedles For Therapeutic Gene Delivery

October 7, 2020

Researchers develop a minimally invasive biodegradable microneedle patch as a novel delivery mode for gene therapy applications

(LOS ANGELES) - There is great potential in gene therapy for treating certain types of cancer and genetic defects, immunological diseases, wounds and infections. The therapies work by delivering genes into the patients' cells, which then produce therapeutic proteins to treat the affliction.

When determining the method of delivery for these genes, there are advantages to choosing a local, rather than systemic delivery of the genetic material. With systemic delivery, there is the possibility of unwanted tissue accumulation or of the genetic material becoming unstable. It is also advantageous to target the skin as a site for local delivery, as it is easily accessible and contains fluid and lymph vessels, as well as immune cells upon which the genetic material can act to initiate treatment.

Terasaki Institute Welcomes New Director

Septemer 23, 2020

(LOS ANGELES) - The Terasaki Institute for Biomedical Innovation welcomes its Director and CEO, Ali Khademhosseini, PhD, who joins the institute with extensive research and leadership experience in the field of biomedical technology.  He is formerly a Professor of Bioengineering at the University of California Los Angeles (UCLA) and a Professor at Harvard Medical School/MITHe is joining the institute from Amazon, Inc, where he recently completed his sabbatical.  He is recognized as a world-renowned leader in combining micro- and nano-engineering approaches with advanced biomaterials for regenerative medicine applications and has authored over 600 peer-reviewed journal papers.  In addition, Dr. Khademhosseini is a co-founder and Scientific Board Member of Obsidio, Incorporated, a biomaterials technology startup company. 

The Transplant Research and Education Center (TREC) Offers a Tailored Education System to Benefit Kidney Transplant Patients

September 16, 2020

Researchers find their computer-tailored education system, Your Path to Transplant” increases knowledge and readiness to pursue kidney transplant  

(LOS ANGELES) – Patients with chronic kidney disease and end-stage renal disease have to go to a dialysis center for hours at a time, several times a week for the rest of their lives. Patients on dialysis have strict dietary restrictions, and have difficulty maintaining a job or school with all of the hours that are spent at the dialysis center each week. Often, dialysis is the main treatment doctors tell patients about, so patients go along with it. However, a living donor kidney transplant is the most effective treatment for end-stage renal disease.  Past research has shown that doctors typically spend about a half an hour giving patients  large quantities of information all at once about transplantation, which causes patients to become overwhelmed with the decision.  

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