Excerpt from Clinical Transplants 2012
An Analysis of Intestinal Transplant in the United States
Toshiyuki Sasaki Terasaki Foundation Laboratory, Los Angeles, California
The results of intestinal transplantation have significantly improved over the past decade. In 1998, the 1 -year adjusted allograft survival was 69 %. In 2007, the 1 -year adjusted allograft survival improved to 79% (1). Nevertheless, the overall graft survival rate, early post - transplant graft survival, and number of patients are still lower than transplantation of other organs. In order to improve the prognosis, medical treatment based on more exact and detailed information is required. In this chapter, we analyze the reasons for allograft failure, the changes in intestinal transplant over the years, and the essential factors about each method of operation for intestinal transplantation [intestine alone versus intestine with other organ(s)]. The purpose of this analysis is to gain greater insight and ultimately to improve transplant outcomes.