Baseline Donor-Specific Antibody Levels and Outcomes in Positive Crossmatch Kidney Transplantation


Gloor JM, Winters JL, Cornell LD, Fix LA, DeGoey SR, Knauer RM, Cosio FG, Gandhi MJ, Kremers W, Stegall MD


The strength of DSA, measured by MFI using single antigen beads, correlates with the incidence of AMR. Positive CDC-XM patients with the highest MFI displayed the highest incidence of AMR, followed by patients with FC-XM>300 and FC-XM<300. Also, lower AMR-free survival was observed in patients with preformed DSA over 10 000, compared to patients with lower MFI.