TFLBUILDING

Pretransplant Donor-Specific Antibodies in Cytotoxic Negative Crossmatch Kidney Transplants: Are They Relevant?

 

Gupta A, Iverson V, Varagunam M, Bodger S, Sinnott P, Thuraisingham RC

http://www.ncbi.nlm.nih.gov/pubmed/18431242

 

The presence of preformed DSA had no impact on delayed graft function, incidence of AMR or one-year graft survival, but a tendency toward lower 5-year graft survival was seen. A multivariate analysis demonstrated a six-fold increased risk of graft failure in DSA positive patients.