TFLBUILDING

Transplant Glomerulopathy: Risk and Prognosis Related to Anti-Human Leukocyte Antigen Class II Antibody Levels

 

Issa N, Cosio FG, Gloor JM, Sethi S, Dean PG, Moore SB, DeGoey S, Stegall MD

http://www.ncbi.nlm.nih.gov/pubmed/18791449

 

Only the presence of preformed DSA against class II showed a risk association for development of transplantglomerulopathy (TG). The higher the MFI, the greater the risk. There was also an association between highMFI and C4d staining, and patients with C4d positive and TG showed the lowest graft survival.