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15th International Histocompatibility Workshop
POST-TRANSPLANT ANTIBODY AND CHRONIC REJECTION NEWSLETTER NO. 2. May 2007
The workshop study now has 69 participating centers as you see in the table next page. The centers listed first have sent in their registered patients. We hope the other centers are making progress in collecting sera and patient data on their patients. Any patient who is more than 6 months posttransplant (regardless of tx date) with currently functioning graft can be enrolled in the study.
In the new 15th WS project, the focus will be placed on hearts, lungs and livers. The analysis from the 13th and 14th WS, despite small numbers, showed a striking association of HLA antibodies to graft loss in Heart and Lung, as shown below and published in our Clinical Transplants 2006 book.
Contributed by: Semana, Kamoun, Leech, LeFor, Poli, Schoenemann, Von Glehn
Contributed by: Reinsmoen. Zeevi, Granita, Kamoun, Alonso
To solidify these results, we hope to study many more patients of heart, lung, liver, and intestinal transplants.Kidneys and Kidney/Pancreas: From the prior 2 workshops, we know that patients will have a lower graft survival if they had antibodies as compared to those without antibodies. This time, we will focus on the specificity of the antibodies (DSA and NDSA), and most importantly, whether these antibodies can be removed. The first attempt should be by increasing current drugs. Failing that, change to various other drugs should be attempted (Myfortic, retuxan, ivIgG, plasmapheresis, etc).
We hope that you will email us your patient list soon to
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, so that we can arrange to send you the screening kits to test HLA and MICA antibodies.
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15th IHIWS Chronic Rejection Study Participants
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As of 5/22/07
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Country
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City
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Last
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Organ
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Patient Form
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1
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Mexico
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Mexico City
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Alberú /Morales
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KD
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1/27/2007
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2
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Italy
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Padova
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Cozzi
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KD
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10/17/2006
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3
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Japan
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Nagoya
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Kobayashi
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KD
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12/28/2006
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4
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USA
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Dallas
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Meyer
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LU
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5/14/2007
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5
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USA
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Los Angeles
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Barba
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KD
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|
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6
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USA
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San Francisco
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Baxter-Lowe
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HT, LU
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|
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7
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France
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Nantes
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Bignon
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KD
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|
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8
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Brazil
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Maringa
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Borelli
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KD
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|
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9
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U.K.
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Birmingham
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Briggs
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KD
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|
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10
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Canada
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Edmonton
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Campbell
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KD, HT, LU
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|
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11
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Poland
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Warsaw
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Cizcek
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KD
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|
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12
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U.K.
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Leeds
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Clarke
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KD
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|
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13
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Italy
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Turin
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Conca
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KD
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|
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14
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Brazil
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Covolo/Marcos
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KD
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|
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15
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USA
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Nashville
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Crowe
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KD
|
|
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16
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USA
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CT
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Cuchara/Stavropoulos
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KD
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|
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17
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France
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Lille
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Dufosse
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KD
|
|
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18
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New Zealand
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Auckland
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Dunn
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KD
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|
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19
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USA
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Salt Lake City
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Eckels/Fuller
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|
|
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20
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Spain
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Barcelona
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Ercilla
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KD
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|
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21
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USA
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Denver
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Freed/Chan
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KD
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|
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22
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U.K.
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Oxford
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Fuggle
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KD/P
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|
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23
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France
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Paris
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Gautreau
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KD
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|
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24
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USA
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Atlanta
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Gebel/Bray
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HT, LU, LV
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|
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25
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Brazil
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Sao Paulo
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Gerbase-De Lima
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KD
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|
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26
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Brazil
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Paraná
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Glehn
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KD
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|
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27
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Mexico
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Guadalajara
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Gomez-Navarro
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KD
|
|
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28
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U.K.
|
Sheffield
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Harmer
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KD
|
|
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29
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U.K.
|
Newcastle
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Howell
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KD
|
|
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30
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Greece
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Athens
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Iniotaki
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KD
|
|
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31
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Japan
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Tokyo
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Ishida/Tanabe
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KD
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|
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32
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USA
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Philadelphia
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Kamoun
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KD, HT
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|
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33
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USA
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Richmond
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Kimball
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KD
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|
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34
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Thailand
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Bangkok
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Kupatawintu
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KD
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|
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35
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USA
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Philadelphia
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Leech
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HT
|
|
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36
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USA
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Tampa
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LeFor
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KD
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|
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37
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U.K.
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Manchester
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Martin
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KD
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|
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38
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USA
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Philadelphia
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McAlack
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KD
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|
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39
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India
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New Delhi
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Mehra/Panigrahi
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KD
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|
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40
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Brazil
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Londrina
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Mocelin
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KD
|
|
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41
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Spain
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Murcia
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Muro
|
KD
|
|
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42
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Bulgaria
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Sofia
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Naumova
|
KD
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|
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43
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Brazil
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Salvador Bahia
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Neumann/Michelon
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KD
|
|
|
44
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USA
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Dallas
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Nikaein
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KD
|
|
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45
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USA
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Portland
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Norman
|
KD
|
|
|
46
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Brazil
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Sao Paulo
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Panajotopoulos
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KD
|
|
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47
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USA
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Springfield
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Pancoska
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HT
|
|
|
48
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Brazil
|
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Pereira
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KD
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|
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49
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Italy
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Rome
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Piazza/Adorno
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KD
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|
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50
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USA
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San Antonio
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Pollack
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KD
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|
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51
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Japan
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Osaka
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Sada
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KD
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52
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U.K.
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Tooting
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Sage
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KD
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|
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53
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USA
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Chapel Hill
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Schmitz
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KD
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|
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54
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Germany
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Berlin
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Schonemann
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KD, HT, LU
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|
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55
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France
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Rennes
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Semana
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KD
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|
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56
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U.K.
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London
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Shaw
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KD
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|
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57
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Italy
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Palermo
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Sireci
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KD, LV
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|
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58
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Czech Rep
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Prague
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Slavcev
|
KD
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|
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59
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USA
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New Orleans
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Stewart
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HT
|
|
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60
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USA
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Chicago
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Tambur
|
HT
|
|
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61
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Brazil
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Sao Paulo
|
Torres
|
KD
|
|
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62
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Mexico
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Monterrey
|
Valdes Cepeda
|
KD
|
|
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63
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Netherlands
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Maastricht
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Van den Berg-Loonen
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KD
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|
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64
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U.K.
|
London
|
Vaughn
|
KD
|
|
|
65
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Thailand
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Bangkok
|
Vejbaesya
|
KD
|
|
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66
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U.K
|
Bristol
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Younie
|
|
|
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67
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USA
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Baltimore
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Zachary
|
HT
|
|
|
68
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USA
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Denver
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Zamora
|
LU
|
|
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69
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USA
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Pittsburgh
|
Zeevi
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KD, LU
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